The serum levels of alkaline phosphatase and total protein of the treated animals were not significantly increased. Sub-chronic administration of the extract significantly increased the serum levels of alanine aminotransaminase and aspartate aminotransaminase, which are indicative of liver damage. The quantity of iron detected from dried crude was 8.92 mg/100 g, while lead and cadmium were non-detectable.
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The phytochemical screening of extract revealed the presence of high amount of tannins, moderate saponins and trace of free reducing sugars. Toxicity profiles of the extract on some liver function parameters were evaluated following a sub-chronic oral administration at doses of 1.44 and 2.87 g/kg. The phytochemical compositions and acute toxicity of the extract were determined also. The inner stem bark of Anacardium occidentale was extracted with 80 % methanol and quantitatively analysed for antinutrients and some heavy metals. These have necessitated the assessment of the toxicity of this plant extract in sub-chronic administration. The extracts of Anacardium occidentale have been used in the management of different cardiovascular disorders in Nigeria. Sub-chronic Hepatotoxicity of Anacardium occidentale (Anacardiaceae) Inner Stem Bark Extract in Rats The most potent extracts are non toxic to mice. The phytochemical investigation of test extracts showed the presence of phenols namely cordol, cardanol and anacardic acid by TLC studies. To Study the anthelmintic activity, the addition of piperine to the formulation significantly enhances the activity.
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occidentale in petroleum ether, dichloromethane: methanol showed better activities compared to A.
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The antifeedant and anthelmintic activities of crude extracts of the shells of Anacardium occidentale were studied by comparing it's activity with the activity of Azadirachta indica A Juss (Kernel), a commercial standard. ON THE ANTIFEEDANT AND ANTHELLMINTIC POTENTIAL OF ANACARDIUM OCCIDENTALE L.